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Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells

✍ Scribed by Osamu Ikeda; Akihiro Mizushima; Yuichi Sekine; Chikako Yamamoto; Ryuta Muromoto; Asuka Nanbo; Kenji Oritani; Akihiko Yoshimura; Tadashi Matsuda

Book ID
108586987
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
455 KB
Volume
102
Category
Article
ISSN
1347-9032

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## Abstract Signal transducers and activators of transcription (STATs) are latent cytoplasmic transcription factors that are activated and translocated into the nucleus after phosphorylation at a conserved tyrosine residue. Mouse model studies have demonstrated that activated Stat5a acts as a criti