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Involvement of Specific Caspases in Motoneuron Cell Deathin Vivoandin VitroFollowing Trophic Factor Deprivation

โœ Scribed by Ling Li; David Prevette; Ronald W. Oppenheim; Carolanne E. Milligan


Book ID
115637538
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
363 KB
Volume
12
Category
Article
ISSN
1044-7431

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PC12 cells are a useful model system for studying neuronal apoptosis. Like neurons, they undergo apoptosis when deprived of trophic support. Involvement of caspases [interleukin 1โค-converting enzyme (ICE)related proteases] has been implicated in apoptosis induced by various stimuli in many cell type