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Involvement of reactive oxygen species-independent mitochondrial pathway in gossypol-induced apoptosis

✍ Scribed by De-Xing Hou; Takuhiro Uto; Xuhui Tong; Toru Takeshita; Shunsuke Tanigawa; Izumi Imamura; Takashi Ose; Makoto Fujii


Book ID
116177072
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
553 KB
Volume
428
Category
Article
ISSN
0003-9861

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Involvement of reactive oxygen species a
✍ Yen-Chou Chen; Shoei-Yn Lin-Shiau; Jen-Kun Lin πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 315 KB πŸ‘ 2 views

Recent studies indicate that arsenic may generate reactive oxygen species to exert its toxicity. However, the mechanism is still unclear. In this study, we demonstrate that arsenite is able to induce apoptosis in a concentration-and time-dependent manner; however, arsenate is unable to do so. An inc