Cisplatin treatment of rats results into a significant increase in the activity of Ca(2+)-independent nitric oxide synthase (NOS) in kidneys and liver. Significant enhancement of lipid peroxidation in gastric mucosa, kidneys and liver was also observed. The administration of NG-nitro-L-arginine meth
β¦ LIBER β¦
Involvement of Ras in Survival Responsiveness to Nitric Oxide Toxicity in Pheochromocytoma Cells
β Scribed by Hyun Sik Jeong; Seong Won Kim; Kwang Jin Baek; Hee Sung Lee; Nyoun Soo Kwon; Young-Myeong Kim; Hye-Young Yun
- Book ID
- 110397733
- Publisher
- Springer US
- Year
- 2002
- Tongue
- English
- Weight
- 150 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0167-594X
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## Abstract ## Background Nitric oxide (NOΒ·) derived from donor drugs has been shown to be an effective chemosensitizer __in vitro__. We investigated the combination of inducible nitric oxide synthase (iNOS) gene transfer, driven by a strong constitutive promoter (cytomegalovirus; CMV) with the DN