In vitro and in vivo induction of heme o
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Yoshihisa Kitamura; Muneki Furukawa; Yasuji Matsuoka; Ikuo Tooyama; Hiroshi Kimu
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Article
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1998
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John Wiley and Sons
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English
โ 552 KB
To determine whether heme oxygenase-1 (HO-1) protein is induced by endogenous nitric oxide (NO) in rat glial cultures, we examined the effects of lipopolysaccharide (LPS), interferon-โฅ (IFN-โฅ), and NO donors such as S-nitroso-N-acetylpenicillamine (SNAP), in mixed glial cells and in vivo rat hippoca