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Involvement of protein kinase C in taxol-induced polyploidization in a cultured sarcoma cell line

✍ Scribed by Zhi-ping Zong; Kohzaburo Fujikawa-Yamamoto; Ai-li Li; Nobuo Yamaguchi; Yi-gang Chang; Manabu Murakami; Yoshimaro Ishikawa

Book ID
114012929
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
437 KB
Volume
394
Category
Article
ISSN
0014-2999

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## Abstract Molecular mechanisms underlying chemotherapeutic agent–induced apoptosis in sarcoma cells are not well known. Induction of apoptosis is regulated by several components including mitogen‐activated protein kinases (MAPKs) comprising ERK, p38MAPKs, and c‐Jun N‐terminal kinase (JNK). In the