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Involvement of protein kinase C in the proliferation of cultured Schwann cells

✍ Scribed by Takeo Yoshimura; Shuichiro Goda; Takuro Kobayashi; Ikuo Goto

Book ID: 115803889
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 553 KB
Volume: 617
Category: Article
ISSN: 0006-8993
DOI: 10.1016/0006-8993(93)90612-q

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Phorbol 12-myristate 13-acetate (PMA) has been shown to stimulate DNA synthesis and cell proliferation in a population of glial cells isolated from newborn rat brain. The non-tumor promoter 4a-phorbol l2,13-didecanoate (4a-PDD), on the other hand, was without an effect. The cultures treated with PMA