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Involvement of p53, nuclear factor κB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines

✍ Scribed by Ya-Ling Hsu; Po-Lin Kuo; Lien-Chai Chiang; Chun-Ching Lin


Book ID
116333137
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
425 KB
Volume
213
Category
Article
ISSN
0304-3835

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✍ Eui-Cheol Shin; Jeon-Soo Shin; Jeon-Han Park; Hoguen Kim; Se-Jong Kim 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 136 KB 👁 3 views

It has been postulated that tumor cells expressing Fas ligand (FasL) can evade immune surveillance by inducing apoptosis in T cells expressing Fas. In this study, we investigated FasL expression in 13 human hepatoma cell lines. Strong FasL expression was detected by reverse transcriptionpolymerase c