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Involvement of Osteopontin in the Matrix-Degrading and Proangiogenic Changes Mediated by Nicotine in Pancreatic Cancer Cells

โœ Scribed by Melissa Lazar; Jennifer Sullivan; Galina Chipitsyna; Qiaoke Gong; Chee Y. Ng; Ahmed F. Salem; Tamer Aziz; Agnes Witkiewicz; David T. Denhardt; Charles J. Yeo; Hwyda A. Arafat


Book ID
107412009
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
747 KB
Volume
14
Category
Article
ISSN
1091-255X

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Induction of osteopontin expression by n
โœ Galina Chipitsyna; Qiaoke Gong; Rathai Anandanadesan; Amer Alnajar; Surinder K. ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 460 KB ๐Ÿ‘ 1 views

## Abstract Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with etiological association with cigarette smoking. Nicotine, an important component of cigarettes, exists at high concentrations in the bloodstream of smokers. Osteopontin (OPN) is a secreted phosphoprotein that confers on can