๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation

โœ Scribed by T. S. Tracy; C. Marra; S. A. Wrighton; F. J. Gonzalez; K. R. Korzekwa

Book ID
105922668
Publisher
Springer
Year
1997
Tongue
English
Weight
191 KB
Volume
52
Category
Article
ISSN
0031-6970

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Involvement of multiple cytochrome P450
Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation
โœ T. S. Tracy; C. Marra; S. A. Wrighton; F. J. Gonzalez; K. R. Korzekwa ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Springer ๐ŸŒ English โš– 191 KB

## Objective: A series of studies was undertaken to determine the cytochrome p450 isoform(s) involved in naproxen demethylation and whether this included the same isoforms reported to be involved in the metabolism of other nsaids. ## Methods: (s)-naproxen was incubated with human liver microsomes