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Involvement of matrix metalloproteinases in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cells in vitro

✍ Scribed by Arnaud Monvoisin; Jean Rosenbaum


Book ID
119527163
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
167 KB
Volume
34
Category
Article
ISSN
0168-8278

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Involvement of matrix metalloproteinase
✍ Arnaud Monvoisin; ChristΓ¨le Bisson; Karim Si-Tayeb; Charles Balabaud; Alexis Des πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 141 KB

## Abstract Intra‐hepatic invasion is a key feature of hepatocellular carcinoma (HCC) progression. We have shown that human liver myofibroblasts induce invasion of HCC cells through Matrigel, via the secretion of hepatocyte growth factor (HGF). In our study, we investigated the role of matrix metal