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Direct evidence that hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells is mediated by urokinase

✍ Scribed by Arnaud Monvoisin; Véronique Neaud; Victor De Lédinghen; Liliane Dubuisson; Charles Balabaud; Paulette Bioulac-Sage; Alexis Desmoulière; Jean Rosenbaum


Book ID
118568977
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
690 KB
Volume
30
Category
Article
ISSN
0168-8278

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Involvement of matrix metalloproteinase
✍ Arnaud Monvoisin; Christèle Bisson; Karim Si-Tayeb; Charles Balabaud; Alexis Des 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 141 KB

## Abstract Intra‐hepatic invasion is a key feature of hepatocellular carcinoma (HCC) progression. We have shown that human liver myofibroblasts induce invasion of HCC cells through Matrigel, via the secretion of hepatocyte growth factor (HGF). In our study, we investigated the role of matrix metal