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Involvement of MAPK pathways in induced apoptosis and the upregulation of cyclooxygeanase-2 by the COX-2 selective inhmitor NS-398 in human colorectal tumor cell lines

✍ Scribed by Douglas J. Elder; Dawn E. Halton; Christos Paraskeva


Book ID
119425407
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
140 KB
Volume
118
Category
Article
ISSN
0016-5085

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Apoptosis induction and cyclooxygenase-2
✍ Douglas J.E. Elder; Dawn E. Halton; Tracey E. Crew; Christos Paraskeva πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 226 KB πŸ‘ 2 views

We determined the effect of the highly selective cyclooxygenase-2 (COX-2) inhibitor NS-398 on proliferation, apoptosis and COX-2 regulation in 3 pre-malignant human colorectal adenoma cell lines (RG/C2, AA/C1, RR/C1) and compared its effect on 3 colorectal carcinoma cell lines (HT29, KS, JW2). COX-2