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Involvement of linker for activation of T cells in the costimulatory signaling pathways

โœ Scribed by M Tsuchida; K Takai; M.M Hamawy; S.J Knechtle; K Naito


Book ID
117233067
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
87 KB
Volume
35
Category
Article
ISSN
0041-1345

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Estrogen (E2)-induced immunomodulation involves dual effects on antigen-presenting cells (APC) and CD4(+)CD25(+) regulatory T cells (Treg) but not a direct effect on effector T cells. In this report, we further investigated the effects of E2 on APC and Treg function. We found that E2 treatment in vi