The INK4A gene, localized to human chromosome 9p21, encodes p16 INK4A , a tumor suppressor that functions at least in part through the inhibition of CDK4, a cyclin-dependent kinase encoded by a gene at 12q13. To examine INK4A gene alterations in uncultured samples of osteosarcoma and the relationshi
Involvement of INK4A gene products in the pathogenesis and development of human osteosarcoma
β Scribed by M. Serena Benassi; Lara Molendini; Gabriella Gamberi; Giovanna Magagnoli; Paola Ragazzini; Giuliana A. Gobbi; Luca Sangiorgi; Laura Pazzaglia; Julia Asp; Camilla Brantsing; Piero Picci
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 469 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0008-543X
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