## Abstract Detoxication of organophosphorus (OP) compounds is affected by genetic and environmental modulation of a number of enzymes involved in the process. For organophosphorothioate insecticides, different P450 isozymes and variants carry out two reactions that have quite different consequence
Involvement of cytochrome P450 1A in sanguinarine detoxication
✍ Scribed by Jiřı́ Vrba; Pavel Kosina; Jitka Ulrichová; Martin Modrianský
- Book ID
- 119377902
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 240 KB
- Volume
- 151
- Category
- Article
- ISSN
- 0378-4274
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📜 SIMILAR VOLUMES
In Table 1, the heading "Isozyme" was inadvertently added to column 1 of Table 1. As is clear from the table caption, the designations listed in this column refer to the donors for the liver microsomes being tested and no heading was intended or necessary.
## Abstract To maximize redox coupling efficiency with recombinant cytochrome P450 hydroxylases from yew (__Taxus__) species installed in yeast for the production of the anticancer drug Taxol, a cDNA encoding NADPH:cytochrome P450 reductase from __T. cuspidata__ was isolated. This single‐copy gene