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Involvement of cell-cell and cell-matrix interactions in bone destruction induced by metastatic MDA-MB-231 human breast cancer cells in nude mice

✍ Scribed by Hiroaki Nakamura; Toru Hiraga; Tadashi Ninomiya; Akihiro Hosoya; Noboru Fujisaki; Toshiyuki Yoneda; Hidehiro Ozawa


Publisher
Springer
Year
2008
Tongue
English
Weight
452 KB
Volume
26
Category
Article
ISSN
0914-8779

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MDA-MB-231 (MDA-231) human breast cancer cells have a high proliferation rate, lack the estrogen receptor, express the intermediate filament vimentin, the hyaluronan receptor CD44, and are able to form tumors in nude mice. The MDA-231 cell line has been used in our laboratory to examine the role of