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Involvement of Ca2+ in platelet-derived growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts

✍ Scribed by Terutaka Tsuda; Kozo Kaibuchi; Brian West; Yoshimi Takai


Book ID
115917476
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
341 KB
Volume
187
Category
Article
ISSN
0014-5793

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## Abstract Mitogenic stimulation of density‐arrested C3H 10T1/2 mouse fibroblasts by serum or purified platelet‐derived growth factor (PDGF) was potently inhibited by retinyl acetate (RAc; IC~50~ = 0.1 ΞΌg/ml, 0.3 Γ— 10^βˆ’6^ M) when administered during the frist 2 hours of mitogen exposure. This inhi