Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cells
โ Scribed by Appierto, V; Villani, M G; Cavadini, E; Lotan, R; Vinson, C; Formelli, F
- Book ID
- 110016670
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 255 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1350-9047
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Taxol is extensively used clinically for chemotherapy of patients with ovarian, breast, and lung cancer. Although taxol induces apoptosis of cancer cells, its exact mechanism of action is not yet known. To determine the mechanism of action of taxol in ovarian cancer, we tested the effec
We previously reported that fenretinide (4HPR) is effective against a human ovarian carcinoma xenografted in nude mice. The effects of 4HPR on ovarian tumors have been further studied in in vitro ovarian carcinoma cell lines A2780, IGROV-I, SW626 and OVCA432. A2780 was the most sensitive line: 50% g