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Investigations into the cine-Amination of 4-Substituted-5-bromopyrimidines by potassium amide in liquid ammonia

✍ Scribed by C. A. H. Rasmussen; H. C. Van Der Plas; P. Grotenhuis; A. Koudijs


Book ID
112125425
Publisher
Journal of Heterocyclic Chemistry
Year
1978
Tongue
English
Weight
396 KB
Volume
15
Category
Article
ISSN
0022-152X

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## Abstract Reaction of 6‐chloro‐ and 6‐(methylthio)purine with potassium amide in liquid ammonia leads to the formation of adenine. When these aminations are carried out with ^15^N‐labelled potassium amide, the ^15^N label is found to be present in the amino group, proving that these reactions do