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Investigation of the stereochemistry of cycloheximide and its degradation products

โœ Scribed by Howard J. Schaeffer; Vijay K. Jain


Publisher
John Wiley and Sons
Year
1963
Tongue
English
Weight
371 KB
Volume
52
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES


Investigation of the stereochemistry of
โœ Howard J. Schaeffer; Vijay K. Jain ๐Ÿ“‚ Article ๐Ÿ“… 1964 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 361 KB

Cycloheximide has been converted by a series of reactions into a dideoxycycloheximide which was found to be optically active. This observation establishes that the methyl groups in dideoxycyclohrximide are oriented in a trans manner. The significance of this result and an interpretation of the stere

Determination of cycloheximide and its d
โœ Edward R. Garrett; Robert E. Notari ๐Ÿ“‚ Article ๐Ÿ“… 1965 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 381 KB

## Glutarimide cyclohexanone @-acetaldehyde Scheme I1 Neither method can distinguish between cycloheximide and its dehydration product, anhydrocycloheximide (Scheme I), an a,p-unsaturated ketone (3). The first method is not capable of differentiating among imides, one of which could be glutarimide