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Determination of cycloheximide and its degradation products alone and in mixtures

✍ Scribed by Edward R. Garrett; Robert E. Notari

Publisher
John Wiley and Sons
Year
1965
Tongue
English
Weight
381 KB
Volume
54
Category
Article
ISSN
0022-3549

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✦ Synopsis

Glutarimide cyclohexanone @-acetaldehyde Scheme I1

Neither method can distinguish between cycloheximide and its dehydration product, anhydrocycloheximide (Scheme I), an a,p-unsaturated ketone (3). The first method is not capable of differentiating among imides, one of which could be glutarimide 8-acetaldehyde, a dealdolization product (3, 4), as per Scheme 11.

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