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Investigation of the Nucleophilic Rearrangement of 2-(Cyanomethyl)-1,4,6-trimethylpyrimidinium Iodide into 4,6-Dimethyl-2-methylaminonicotinic Acid Nitrile.

โœ Scribed by G. G. Danagulyan; L. G. Sahakyan; D. A. Tadevosyan


Publisher
John Wiley and Sons
Year
2004
Weight
14 KB
Volume
35
Category
Article
ISSN
0931-7597

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โœฆ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


๐Ÿ“œ SIMILAR VOLUMES


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## Abstract Filicinic acid (5) was prepared in 75โ€80% overall yield from 4,4โ€dimethylโ€2โ€cyclohexenone (1). The key intermediate, tetrachlorodienone 2, underwent facile substitution of both ฮฒโ€chlorine substituents by methoxide affording the bis enol ether 3 which was converted into dichlorofilicinic