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Investigation of the kinetic and stereochemical recognition of arene and azaarene oxides by isozymes A2 and C2 of glutathione S-transferase

✍ Scribed by Charles C. Boehlert; Richard N. Armstrong

Book ID: 115757616
Publisher: Elsevier Science
Year: 1984
Tongue: English
Weight: 400 KB
Volume: 121
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(84)90773-3

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## Abstract Glutathione __S__‐transferases (GSTs) are a family of detoxifying enzymes that catalyze the conjugation of glutathione (GSH) to electrophiles, thereby increasing the solubility of xenobiotics and aiding its excretion from the cell. The present work presents the inhibition of a mu‐class