## Abstract Complexes of proflavine with DNA and deoxyribonucleohistone from calf thymus show different optical activity in the visible and the ultraviolet. Although the visible CD spectra of both complexes arise from interactions of dye molecules, the variation in the optical activity with the amo
Investigation of the Interactions of β-Peptides with DNA Duplexes by Circular Dichroism Spectroscopy
✍ Scribed by Kenji Namoto; James Gardiner; Thierry Kimmerlin; Dieter Seebach
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- German
- Weight
- 914 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
University of Stellenbosch, on the occasion of his 65th birthday
📜 SIMILAR VOLUMES
## Abstract Pexiganan (Gly–Ile–Gly–Lys–Phe–Leu–Lys–Lys–Ala–Lys–Lys–Phe–Gly–Lys–Ala–Phe–Val–Lys–Ile–Leu–Lys–Lys), a 22 amino acid peptide, is an analogue of the magainin family of antimicrobial peptides present in the skin of the African clawed frog. Conformational analysis of pexiganan was carried
Absorption, circular dichroism (CD), and UV resonance Raman (UVRR) spectroscopies were applied to selectively examine the environmental and structural changes of Trp and Tyr residues in the phosphatidylinositol 3-kinase (PI3K) SH3 domain induced by ligand association. Comparison of the spectra of PI
## Abstract Inspired by naturally occurring DNA‐binding proteins and their artificial __α__‐peptidic mimics reported to date, a research project was initiated aiming at creating a new class of __β__‐peptides capable of binding to and ultimately regulating the functions of DNA. As an initial foray,
## Abstract The interaction with DNA of a peptide nucleic acid (PNA) oligomer (16nt) conjugated with a nuclear localization signal (NLS) peptide, which was previously found to be able to inhibit tumor cell proliferation through block of transcription of the __MYCN__ oncogene, was studied by UV and