✦ LIBER ✦

Investigation of the competition of two ligands for the same binding sites on a protein

✍ Scribed by Nicole Lecureuil; Janine Trochet; Lucette Garreau; Gérard Crouzat-Reynes; Michel Lecureuil

Book ID: 107714337
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 419 KB
Volume: 159
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(86)90359-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Graphical analysis of binding data refle

Graphical analysis of binding data reflecting competition between two ligands for the same acceptor sites

✍ Simon J. Harris; Donald J. Winzor 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 722 KB

A theoretical expression is derived for the analysis of results from competitive binding studies in which two multivalent ligands compete for acceptor sites, and a linear transform is suggested for simple graphical representation and assessment of experimental results. The protocol is illustrated by

Spectroscopic investigations on the bind

Spectroscopic investigations on the binding site of bovine hepatic fatty acid binding protein. Evidence for the existence of a single binding site for two fatty acid molecules

✍ Hermann J.K. Keuper; Roger A. Klein; Friedrich Spener 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 713 KB

Investigation of the copper binding site

Investigation of the copper binding sites in the Menkes disease protein, ATP7A

✍ P. Y. Jensen; N. Bonander; B. G. Karlsson; N. Horn; Z. Tümer; O. Farver 📂 Article 📅 1998 🏛 Springer 🌐 English ⚖ 168 KB

Methods for the analysis of the kinetics

Methods for the analysis of the kinetics of cooperative binding of ligands to a two-site lattice

✍ Mary E. Edgerton; Frank A. Handler; Cheng-Wen Wu 📂 Article 📅 1983 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 786 KB

## Abstract Solutions are obtained that describe the time dependence of the reversible binding of a ligand to a two‐site lattice. The binding may be cooperative. Three methods are used to obtain these solutions: the separation of on/off processes with a variable transformation, the asymptotic serie

A quantitative plot for the determinatio

A quantitative plot for the determination of negatively co-operative ligand binding sites in proteins

✍ Julian S. Shindler; Keith F. Tipton 📂 Article 📅 1978 🏛 Elsevier Science 🌐 English ⚖ 327 KB

Competitive binding assays for high-affi

Competitive binding assays for high-affinity binders in the presence of endogenous ligands: Application to biotin-binding proteins

✍ Richard W. Schreiber Jr.; Michael A. Letavic; Timothy J. McGahan; Harold B. Whit 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 731 KB

Endogenous ligands complicate radioligand-binding assays of high-affinity binding proteins by obscuring binding sites or by diluting the labeled ligand. We have developed a mathematical model for such systems where radioligand and endogenous ligand are structurally identical. Data which relate radio