Investigation of glutathioneS-transferase M1 and T1 deletions in lung cancer
β Scribed by Julide Altinisik; Zinnet B. Balta; Gunay Aydin; Turgut Ulutin; Nur Buyru
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 184 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0301-4851
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## Abstract Tobacco smoke and ionizing radiation induce oxidative stress by transmitting or generating reactive oxygen species (ROS). We hypothesized that glutathioneβ__S__βtransferase M1 (__GSTM1__) null homozygotes would have decreased ability to neutralize ROS that might increase their susceptib
## Abstract The aim of this study was to investigate associations between genetic variability in specific Glutathione __S__βtransferases (__GST__) genes (__GSTM1__, __GSTT1__ and __GSTP1__) and susceptibility to breast cancer. Genotypes of blood specimen DNA were determined for 65 women with incide