𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Investigation of experimental approaches to the determination of pKa values by capillary electrophoresis

✍ Scribed by S.J. Gluck; J.A. Cleveland Jr.

Book ID
107785307
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
654 KB
Volume
680
Category
Article
ISSN
1873-3778

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Determination of thermodynamic pKa value
Determination of thermodynamic pKa values of benzimidazole and benzimidazole derivatives by capillary electrophoresis
✍ Gilberto Jerez; Gregory Kaufman; Michael Prystai; Sonja Schenkeveld; Kingsley K. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 577 KB

## Abstract Thermodynamic p__K__~a~ values for benzimidazole and several substituted benzimidazoles were determined by CE. Electrophoretic mobilities of benzimidazoles were determined by CE at different pH levels and ionic strengths. The dependence of electrophoretic mobilities on pH was used to ob

Determination of pKa values by capillary
Determination of pKa values by capillary zone electrophoresis with a dynamic coating procedure
✍ Laurent Geiser; Yveline Henchoz; Alexandra Galland; Pierre-Alain Carrupt; Jean-L πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 465 KB πŸ‘ 1 views

CZE allows to measure the acidic dissociation constant (pKa) of many drug substances. However, determining the EOF intensity may be time-consuming, especially at a low pH. In order to overcome this drawback, a dynamic coating procedure of the capillary was carried out to increase microEOF, and thus