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Determination of pKa values of benzimidazole derivatives from mobility obtained by capillary electrophoresis

✍ Scribed by Emmanuelle Lipka; Marcia Folly-Klan; Julie Charton; Marie-Pierre Vaccher; Jean-Paul Bonte; Claude Vaccher

Book ID
108189808
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
204 KB
Volume
53
Category
Article
ISSN
0731-7085

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Determination of thermodynamic pKa value
Determination of thermodynamic pKa values of benzimidazole and benzimidazole derivatives by capillary electrophoresis
✍ Gilberto Jerez; Gregory Kaufman; Michael Prystai; Sonja Schenkeveld; Kingsley K. πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 577 KB

## Abstract Thermodynamic p__K__~a~ values for benzimidazole and several substituted benzimidazoles were determined by CE. Electrophoretic mobilities of benzimidazoles were determined by CE at different pH levels and ionic strengths. The dependence of electrophoretic mobilities on pH was used to ob