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Investigation of calcitonin (CT) binding to its receptors (CTR) in MCF-7 human breast cancer cell line

✍ Scribed by Vincze, B.; Lőrincz, I.; Pályi, I.; Kerpel-Fronius, S.; Számel, I.; Szántó, I.; Svastics, E.; Sugár, J.

Book ID: 123506674
Publisher: Elsevier Science
Year: 1987
Weight: 244 KB
Volume: 23
Category: Article
ISSN: 0277-5379
DOI: 10.1016/0277-5379(87)90759-0

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## Abstract We show that flavonoids positively regulate type‐II estrogen‐binding site (type‐ll EBS) levels both in MCF‐7 (ER‐positive) and in MDA‐MB231 (ER‐negative) breast‐cancer cells. Type‐ll EBS were measured by a whole‐cell assay at 4°C for 2.5 hr using [^3^H]‐estradiol as tracer. In both cell