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Investigation of 5-Nitrofuran Derivatives: Synthesis, Antibacterial Activity, and Quantitative Structure−Activity Relationships

✍ Scribed by Pires, José Ricardo; Saito, Cristina; Gomes, Suely L.; Giesbrecht, Astréa M.; Amaral, Antonia T-do

Book ID: 118135116
Publisher: American Chemical Society
Year: 2001
Tongue: English
Weight: 106 KB
Volume: 44
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm0101693

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## Abstract Starting from 5‐nitro‐2‐furoyl azide **(1)**, some new 5‐nitro‐2‐furamides **2a–d**, __O__‐alkyl __N__‐(5‐nitro‐2‐furyl)carbamates **3a,b** and 5‐nitro‐2‐ureidofurans **4a,b** were synthesized and tested for in vitro antimicrobial activity. Compounds **2c** and **2d** exhibited apprecia