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Investigation of 15 of the top candidate genes for late-onset Alzheimer’s disease

✍ Scribed by Olivia Belbin; Minerva M. Carrasquillo; Michael Crump; Oliver J. Culley; Talisha A. Hunter; Li Ma; Gina Bisceglio; Fanggeng Zou; Mariet Allen; Dennis W. Dickson; Neill R. Graff-Radford; Ronald C. Petersen; Kevin Morgan; Steven G. Younkin

Publisher: Springer
Year: 2010
Tongue: English
Weight: 226 KB
Volume: 129
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-010-0924-2

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## Abstract ## Background Familial factors are clearly associated with an increased risk of developing late onset Alzheimer's disease (LOAD). However, there is emerging evidence to suggest that familial factors may also influence clinical phenotype. To date, most studies have focussed on familial