## Abstract Availability of human embryonic stem cells (hESC) has enhanced human neural differentiation research. The derivation of neural progenitor (NP) cells from hESC facilitates the interrogation of human embryonic development through the generation of neuronal subtypes and supporting glial ce
Intrinsic transition of embryonic stem-cell differentiation into neural progenitors
โ Scribed by Kamiya, Daisuke; Banno, Satoe; Sasai, Noriaki; Ohgushi, Masatoshi; Inomata, Hidehiko; Watanabe, Kiichi; Kawada, Masako; Yakura, Rieko; Kiyonari, Hiroshi; Nakao, Kazuki
- Book ID
- 109899400
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 988 KB
- Volume
- 470
- Category
- Article
- ISSN
- 0028-0836
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## Abstract The neural crest (NC) is a transient population of multipotent progenitors arising at the lateral edge of the neural plate in vertebrate embryos, which then migrate throughout the body to generate diverse array of tissues such as the peripheral nervous system, skin melanocytes, and cran
Due to advances in stem cell biology, embryonic stem (ES) cells can be induced to differentiate into a particular mature cell lineage when cultured as embryoid bodies. Although transplantation of ES cells-derived neural progenitor cells has been demonstrated with some success for either spinal cord