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Intrinsic susceptibility of the kidney to acetaminophen toxicity in middle-aged rats

โœ Scribed by Tarloff, Joan B.; Goldstein, Robin S.; Silver, Anthony C.; Hewitt, William R.; Hook, Jerry B.


Book ID
122931132
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
655 KB
Volume
52
Category
Article
ISSN
0378-4274

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## Abstract A multiโ€age rat model was evaluated as a means to identify a potential ageโ€related difference in liver injury following exposure to valproic acid (VPA), a known pediatric hepatotoxic agent. Different age groups of Spragueโ€Dawley (SD) rats (10โ€, 25โ€, 40โ€, 80โ€dayโ€old) were administered VP