Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen
✍ Scribed by Otto Kučera; Tomáš Roušar; Pavla Staňková; Lenka Haňáčková; Halka Lotková; Miroslav Podhola; Zuzana Červinková
- Book ID
- 108954210
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 888 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0815-9319
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## Abstract Non‐alcoholic fatty liver disease (NAFLD) is the most common liver disease in developed countries, and accumulating evidence suggests it as the hepatic manifestation of the metabolic syndrome (MS). Although the published prevalence of hepatocellular carcinoma (HCC) is low in NAFLD/NASH
A 67-yr-old man with chronic cardiopulmonary disease exhibited severe hepatic and moderately severe renal injury after short-term ingestion of therapeutic doses of acetaminophen (1 to 3 @day for 3 days). Drug metabolism and other studies, performed 5 mo after recovery from the acute insult, indicate