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Intrinsic Requirement for Zinc Finger Transcription Factor Gfi-1 in Neutrophil Differentiation

✍ Scribed by Hanno Hock; Melanie J Hamblen; Heather M Rooke; David Traver; Roderick T Bronson; Scott Cameron; Stuart H Orkin


Book ID
117723314
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
785 KB
Volume
18
Category
Article
ISSN
1074-7613

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The Myt1 family of transcription factors is unique among the many classes of zinc finger proteins in how the zinc-stabilized fingers contact the DNA helix. To examine the function of Myt1 in the developing nervous system, we generated mice in which Myt1 expression was replaced by an enhanced Green F