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Intrinsic hyporesponsiveness of invariant natural killer T cells precedes the onset of lupus

✍ Scribed by Yang, J.-Q.; Kim, P. J.; Halder, R. C.; Singh, R. R.

Book ID
120238508
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
942 KB
Volume
173
Category
Article
ISSN
0009-9104

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## Abstract ## Objective To investigate the role of invariant natural killer T (iNKT) cells in TNF^__Ξ”ARE/+__^ mice, an animal model of spondylarthritis (SpA) with both gut and joint inflammation. ## Methods The frequency and activation of iNKT cells were analyzed on mononuclear cells from the l