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In vitro expanded human invariant natural killer T-cells promote functional activity of natural killer cells

✍ Scribed by María Moreno; Johan W. Molling; Silvia von Mensdorff-Pouilly; René H.M. Verheijen; B. Mary E. von Blomberg; Alfons J.M. van den Eertwegh; Rik J. Scheper; Hetty J. Bontkes

Book ID
113540661
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
932 KB
Volume
129
Category
Article
ISSN
1090-2341

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## Abstract ## Objective To investigate the role of invariant natural killer T (iNKT) cells in TNF^__ΔARE/+__^ mice, an animal model of spondylarthritis (SpA) with both gut and joint inflammation. ## Methods The frequency and activation of iNKT cells were analyzed on mononuclear cells from the l