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Intravesical administration of 5-aminolevulinic acid (5-ALA) Safety and pharmacokinetics of 5-ALA and its metabolite protoporphyrin IX

✍ Scribed by G. Popken; W. Schultze-Seemann; K.-U. Seiler; M. Birkel; U. Wetterauer

Book ID
105922366
Publisher
Springer
Year
2000
Tongue
English
Weight
120 KB
Volume
56
Category
Article
ISSN
0031-6970

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πŸ“œ SIMILAR VOLUMES

5-aminolevulinic acid (ALA)-induced prot
5-aminolevulinic acid (ALA)-induced protoporphyrin IX fluorescence and photodynamic effects in the rat bladder: An in vivo study comparing oral and intravesical ALA administration
✍ Chang, Shi-Chung; Buonaccorsi, Gio; MacRobert, Alexander J.; Bown, S. G. πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 578 KB

Background and Objective: Photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) for sensitization is a promising treatment for carcinoma in situ and diffuse premalignant changes of the bladder. We studied the biodistribution of PpIX in a range of tissues with

Photobleaching of protoporphyrin IX in c
Photobleaching of protoporphyrin IX in cells incubated with 5-aminolevulinic acid
✍ Johan Moan; Giedre Streckyte; Saulius Bagdonas; Øystein Bech; Kristian Berg πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 208 KB πŸ‘ 2 views

Protoporphyrin IX (Pp IX) is the main photosensitizer in photochemotherapy with 5-aminolevulinic acid (ALA). Pp IX is photolabile and the present work shows that 70-95% of Pp IX in cells is degraded by clinically relevant light exposures (40-200 J cm 22 at 630 nm). During light exposure a small yiel