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Intravenous infusion of mesenchymal stem cells enhances regional perfusion and improves ventricular function in a porcine model of myocardial infarction

โœ Scribed by Michael E. Halkos; Zhi-Qing Zhao; Faraz Kerendi; Ning-Ping Wang; Rong Jiang; L. Susan Schmarkey; Bradley J. Martin; Arshed A. Quyyumi; Walter L. Few; Hajime Kin; Robert A. Guyton; Jakob Vinten-Johansen


Publisher
Springer
Year
2008
Tongue
English
Weight
491 KB
Volume
103
Category
Article
ISSN
0300-8428

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Human Amnion-derived Mesenchymal Stem Cells (hAMSCs) were transplanted into the infarct and periinfarct regions of a pig ischemia-reperfusion model. The hAMSC therapy improved cardiac systolic function post-MI, compared to control animals, and Cardiac MRI with Manganese-Enhanced MRI (MEMRI) was able