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Intrathymic Immunomodulation and the “Infectious” Tolerance Pathway in Allograft Recipients

✍ Scribed by Brian L. Reemtsen; Hirohisa Kato; Tao S. Wang; Ronald W. Busuttil; Jerzy W. Kupiec-Weglinski; John A. Goss

Book ID
115635853
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
177 KB
Volume
84
Category
Article
ISSN
0022-4804

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The CD40 pathway in allograft rejection,
The CD40 pathway in allograft rejection, acceptance, and tolerance
✍ Christian P Larsen; Thomas C Pearson 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 713 KB

The CD40 pathway plays a critical role at many levels of the sensitization and effector phases of allograft rejection. In addition to the important signaling role of this pathway for T cell help and effector function, recent evidence suggests that the CD40 pathway can directly co-stimulate T cells,