๐”– Bobbio Scriptorium
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Intrathecal methotrexate overdoses

โœ Scribed by R Trinkle; JK Wu


Book ID
114811687
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
28 KB
Volume
87
Category
Article
ISSN
0803-5253

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๐Ÿ“œ SIMILAR VOLUMES


Intrathecal methotrexate overdose
โœ ACW Lee; KW Wong; KW Fong; KT So ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 319 KB
Pharmacokinetics and biochemical effects
โœ Lawrence J. Ettinger ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 622 KB

A nine-year-old boy with non-Hodgkin's lymphoma inadvertantly received 54 times the standard dose of intrathecal methotrexate (650 mg vs 12 mg). He sustained an immediate and subsequently fatal necrotizing leukoencephalopathy despite an early cerebrospinal fluid (CSF) exchange, intravenous leucovori