๐”– Bobbio Scriptorium
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Emergency Treatment of Life-Threatening Intrathecal Methotrexate Overdose

โœ Scribed by Yoram Finkelstein; Shoshana Zevin; Judith Heyd; Yedidiah Bentur; Yehezkel Zigelman; Moshe Hersch


Book ID
116779467
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
89 KB
Volume
25
Category
Article
ISSN
0161-813X

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๐Ÿ“œ SIMILAR VOLUMES


Pharmacokinetics and biochemical effects
โœ Lawrence J. Ettinger ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 622 KB

A nine-year-old boy with non-Hodgkin's lymphoma inadvertantly received 54 times the standard dose of intrathecal methotrexate (650 mg vs 12 mg). He sustained an immediate and subsequently fatal necrotizing leukoencephalopathy despite an early cerebrospinal fluid (CSF) exchange, intravenous leucovori