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Intrathecal levels of IL-6 in Alzheimer’s disease

✍ Scribed by Kurt A. Jellinger


Publisher
Springer
Year
2009
Tongue
English
Weight
103 KB
Volume
257
Category
Article
ISSN
0340-5354

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Recently, the neurotoxic amyloid ␤-peptide was shown to up-regulate polyamine metabolism by increasing ornithine decarboxylase (ODC) activity and polyamine uptake by initiating free radical damage in Alzheimer's disease (AD). 1 Because of these findings, polyamines have been considered to play an im