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Intrasphincteric botulinum toxin an alternative therapy for achalasia?

Book ID
120876644
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
1997
Weight
221 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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We investigated the long-term efficacy and safety of intrasphincteric injections of botulinum toxin (100 U) in 57 patients with esophageal achalasia. One month after treatment, 50 patients had improved (88%); both symptom score and LES pressure were significantly reduced (P < 0.001). After a mean fo