Synthesis of [14C]-labelled dihydropyrid
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Howard Parnes; Glenn T. Huang; Emma J. Shelton
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Article
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1988
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John Wiley and Sons
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French
β 376 KB
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The Hantzsch synthesis has been applied to the general prepararion of 4-aryl-dihydropyridines labelled in the metabolically stable 4-position of the dihydropyridine ring. The synthesis is based on the preparation of a key common intermediate, m-nirr~benzaldehyde-[formyl-~~C], in high yield from Ba14