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Intramolecular N-arylation in heterocyclization: synthesis of new pyrido-fused pyrrolo[1,2-a][1,4]diazepinones

✍ Scribed by Loreto Legerén; Domingo Domínguez


Book ID
104097899
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
371 KB
Volume
51
Category
Article
ISSN
0040-4039

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## Abstract The synthesis of the title compounds was achieved using the key intermediate ethyl 4,6‐dimethyl‐3‐(pyrrol‐1‐yl)thieno[2,3‐__b__]pyridine‐2‐ carboxylate 2. This latter compound was obtained __via__ the interaction of the thienopyridine amino ester 1 with 2,5 dimethoxytetrahydrofuran in a