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Intramolecular guanidine epoxide ring opening reactions

✍ Scribed by Mark Dennis; Louise M Hall; Patrick J Murphy; Andrew J Thornhill; Robert Nash; Ana L Winters; Michael B Hursthouse; Mark E Light; Peter Horton

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 577 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)00519-7

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✦ Synopsis

The synthesis of a range of cyclic guanidines via intramolecular ring opening of epoxides or iodocyclisation is reported. A preliminary investigation of the glycosidase inhibitory activity of these substances is also discussed.

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