Intraindividual variations of 8-methoxypsoralen plasma levels
✍ Scribed by M. Schäfer-Korting; H. Ch. Korting
- Publisher
- Springer-Verlag
- Year
- 1981
- Tongue
- English
- Weight
- 442 KB
- Volume
- 272
- Category
- Article
- ISSN
- 0340-3696
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An improved fluorodensitometric assay for the determination of 8methoxypsoralen (8-MOP) in plasma is described. Because of its low limit of detection (below 1 rig/spot) this method is suitable to determine the drug in skin suction blister fluid, too. The standard deviation of the procedure is 6.4 %
A method is described for the determination of 8-methoxypsoralen in human serum using a fluorodensitometric method. The fluorescence densitometry was carried out directly on the thin layer plate. The developing fluid consisted of chloroform/methanol. In patients with psoriasis after oral application