𝔖 Bobbio Scriptorium
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Intrahippocampal LPS injections reduce Aβ load in APP+PS1 transgenic mice

✍ Scribed by Giovanni DiCarlo; Donna Wilcock; Debbi Henderson; Marcia Gordon; Dave Morgan

Book ID
117412237
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
194 KB
Volume
22
Category
Article
ISSN
0197-4580

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## Abstract Memantine is a moderate‐affinity, uncompetitive N‐methyl‐D‐aspartate (NMDA) receptor antagonist that stabilizes cognitive, functional, and behavioral decline in patients with moderate to severe Alzheimer's disease (AD). In AD, the extracellular deposition of fibrillogenic amyloid‐β pept